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Zoltan Farkas et al.
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M. Pastorek et al.
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Suhasini Joshi et al.
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Shujiro Okuda et al.
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Marta Prieto-Vila et al.
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Eduard Batlle et al.
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Tsukasa Shibue et al.
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Florian H. Schopf et al.
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C. Subramanian et al.
NEOPLASIA (2017)
Cancer Stem Cells: Basic Concepts and Therapeutic Implications
Dany Nassar et al.
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To wake up cancer stem cells, or to let them sleep, that is the question
Shoichiro Takeishi et al.
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A Remodeled Hsp90 Molecular Chaperone Ensemble with the Novel Cochaperone Aarsd1 Is Required for Muscle Differentiation
Pablo C. Echeverria et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
The epichaperome is an integrated chaperome network that facilitates tumour survival
Anna Rodina et al.
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Heat Shock Proteins Promote Cancer: It's a Protection Racket
Stuart K. Calderwood et al.
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The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
Mark R. Woodford et al.
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Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors
Mark R. Woodford et al.
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Modifiers of the Genotype-Phenotype Map: Hsp90 and Beyond
Rachel Schell et al.
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Enhanced anticancer activity of a protein phosphatase 2A inhibitor on chemotherapy and radiation in head and neck squamous cell carcinoma
Dong-wang Zhu et al.
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Transcriptome and proteome analysis of Eucalyptus infected with Calonectria pseudoreteaudii
Quanzhu Chen et al.
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A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species
Hongliang Zong et al.
CELL REPORTS (2015)
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models
Luke Whitesell et al.
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Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype
Bojana Gligorijevic et al.
PLOS BIOLOGY (2014)
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies
Utthara Nayar et al.
BLOOD (2013)
iTRAQ protein profile analysis of Citrus sinensis roots in response to long-term boron-deficiency
Lin-Tong Yang et al.
JOURNAL OF PROTEOMICS (2013)
Global quantification of mammalian gene expression control (vol 473, pg 337, 2011)
Bjoern Schwanhaeusser et al.
NATURE (2013)
Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on T-Cell Proteome Have Implications for Anti-Cancer Therapy
Ivo Fierro-Monti et al.
PLOS ONE (2013)
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
Komal Jhaveri et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Inhibition of heat shock protein (Hsp) 27 potentiates the suppressive effect of Hsp90 inhibitors in targeting breast cancer stem-like cells
Che-Hsin Lee et al.
BIOCHIMIE (2012)
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics
Armin Haupt et al.
BMC CANCER (2012)
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Bryan Newman et al.
CANCER RESEARCH (2012)
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Mikko Taipale et al.
CELL (2012)
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Len Neckers et al.
CLINICAL CANCER RESEARCH (2012)
Aneuploidy causes proteotoxic stress in yeast
Ana B. Oromendia et al.
GENES & DEVELOPMENT (2012)
Proteotoxic stress of cancer: Implication of the heat-shock response in oncogenesis
Chengkai Dai et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Quantitative Proteomics Reveals That Hsp90 Inhibition Preferentially Targets Kinases and the DNA Damage Response
Kirti Sharma et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
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Nadezhda T. Doncheva et al.
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Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90
Kamalika Moulick et al.
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An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine
Pablo C. Echeverria et al.
PLOS ONE (2011)
Protein Homeostasis and the Phenotypic Manifestation of Genetic Diversity: Principles and Mechanisms
Daniel F. Jarosz et al.
ANNUAL REVIEW OF GENETICS, VOL 44 (2010)
ATPases as Drug Targets: Insights from Heat Shock Proteins 70 and 90
Andrew J. Massey
JOURNAL OF MEDICINAL CHEMISTRY (2010)
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Gabriela Bindea et al.
BIOINFORMATICS (2009)
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Ji Luo et al.
CELL (2009)
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
Eloisi Caldas-Lopes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor
Sofia Barluenga et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Analysis of Ras-induced oncogenic transformation of NIH-3T3 cells using differential-display 2-DE proteomics
Hong Ji et al.
ELECTROPHORESIS (2007)
Integration of biological networks and gene expression data using Cytoscape
Melissa S. Cline et al.
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Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors
Robert M. Immormino et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Hsp90 potentiates the rapid evotution of new traits: Drug resistance in diverse fungi
LE Cowen et al.
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AL Barabási et al.
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WQ Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
A Kamal et al.
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An automated method for finding molecular complexes in large protein interaction networks
GD Bader et al.
BMC BIOINFORMATICS (2003)
Specificity and stability in topology of protein networks
S Maslov et al.
SCIENCE (2002)
Hypoxia inhibits G1/S transition through regulation of p27 expression
LB Gardner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Molecular assembly of mitogen-activated protein kinase module in ras-transformed NIH3T3 cell line
KS Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2000)
Insulin induces epidermal growth factor (EGF) receptor clustering and potentiates EGF-stimulated DNA synthesis in Swiss 3T3 cells: A mechanism for costimulation in mitogenic synergy
MF Crouch et al.
IMMUNOLOGY AND CELL BIOLOGY (2000)
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