期刊
ORGANIC LETTERS
卷 21, 期 8, 页码 2927-2931出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b00985
关键词
-
资金
- National Natural Science Foundation of China [21871100]
- Fundamental Research Funds for the Central Universities [2017KFYXJJ166]
- Huazhong University of Science and Technology (HUST)
- Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica [BCMM201805]
A novel method for site-selective C-H functionalization of ethyl acetate mediated by pyridine boryl radicals is presented, delivering a variety of 4-phenylbut-3-yn-2-yl acetate derivatives under mild conditions. A distinguishing feature of this reaction is that the pyridine-ligated boryl radicals can abstract the inactive a-hydrogen of the alkoxyl group instead of the a-hydrogen of carbonyl groups described in a previous report using amine-ligated boryl radicals. Significantly, substrates with halogen atoms are compatible under the reaction conditions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据