Nanofabrication based on DNA nanotechnology

Nanofabrication refers to manufacturing objects with nanometer dimensions. The evolution of DNA nano-technology has brought new inspirations to this field, owing to the unprecedented programmability of DNA molecules. By combining with other components, DNA nanostructures can template the growth of heterogeneous materials, support delicate plasmonic devices, build smart drug delivery vehicles and detect biomolecular targets. This article focuses on key strategies for DNA-based nanofabrication and highlights recent developments in chemical reactions confined on DNA nanostructures, including metallization, mineralization and polymer coating. We also review applications based on DNA nanofabrication and propose perspective in this field. (C) 2019 Elsevier Ltd. All rights reserved.