4.6 Review

Recent Advances in Aptamer Discovery and Applications

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Article Biochemistry & Molecular Biology

Selection and characterization of novel DNA aptamer against colorectal carcinoma Caco-2 cells

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BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2019)

Article Nanoscience & Nanotechnology

In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model

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INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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In Vitro Selection of a DNA Aptamer by Cell-SELEX as a Molecular Probe for Cervical Cancer Recognition and Imaging

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JOURNAL OF MOLECULAR EVOLUTION (2019)

Article Biochemistry & Molecular Biology

Aptamer-mediated Plasmodium-specific diagnosis of malaria

Yee-Wai Cheung et al.

BIOCHIMIE (2018)

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Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells

Laia Civit et al.

BIOCHIMIE (2018)

Article Biophysics

A portable microfluidic Aptamer-Tethered Enzyme Capture (APTEC) biosensor for malaria diagnosis

Lewis A. Fraser et al.

BIOSENSORS & BIOELECTRONICS (2018)

Review Biochemistry & Molecular Biology

Key Aspects of Nucleic Acid Library Design for in Vitro Selection

Maria A. Vorobyeva et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Medicine, Research & Experimental

DNA Thioaptamer with Homing Specificity to Lymphoma Bone Marrow Involvement

Junhua Mai et al.

MOLECULAR PHARMACEUTICS (2018)

Article Biotechnology & Applied Microbiology

TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models

Geronimo Fernandez et al.

MOLECULAR THERAPY (2018)

Article Nanoscience & Nanotechnology

An aptamer-enabled DNA nanobox for protein sensing

Marco S. L. Tang et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

Article Biochemistry & Molecular Biology

Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries

Irina Randrianjatovo-Gbalou et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Multidisciplinary Sciences

Aptamers as biomarkers for neurological disorders. Proof of concept in transgenic mice

Soizic Lecocq et al.

PLOS ONE (2018)

Article Medicine, Research & Experimental

Selection of Metastatic Breast Cancer Cell-Specific Aptamers for the Capture of CTCs with a Metastatic Phenotype by Cell-SELEX

Wan-Ming Li et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

Review Pharmacology & Pharmacy

Therapeutic aptamers in discovery, preclinical and clinical stages

Said I. Ismail et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Review Biochemistry & Molecular Biology

Recent developments in cell-SELEX technology for aptamer selection

Harleen Kaur

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2018)

Review Biochemistry & Molecular Biology

SELEX methods on the road to protein targeting with nucleic acid aptamers

Payam Bayat et al.

BIOCHIMIE (2018)

Article Multidisciplinary Sciences

Targeting the polyadenylation factor EhCFIm25 with RNA aptamers controls survival in Entamoeba histolytica

Juan David Ospina-Villa et al.

SCIENTIFIC REPORTS (2018)

Article Medicine, Research & Experimental

Phosphorothioate-Modified AP613-1 Specifically Targets GPC3 when Used for Hepatocellular Carcinoma Cell Imaging

Lili Dong et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

Article Biochemistry & Molecular Biology

Selection, Characterization, and Application of ssDNA Aptamer against Furaneol

Natalia Komarova et al.

MOLECULES (2018)

Review Genetics & Heredity

Advances on Aptamers against Protozoan Parasites

Juan David Ospina-Villa et al.

Article Biochemical Research Methods

Microfluidic platforms for rapid screening of cancer affinity reagents by using tissue samples

Lien-Yu Hung et al.

BIOMICROFLUIDICS (2018)

Review Chemistry, Analytical

Electrochemical Aptasensors for Food and Environmental Safeguarding: A Review

Geetesh Kumar Mishra et al.

BIOSENSORS-BASEL (2018)

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Ultrafine Graphene Nanomesh with Large On/Off Ratio for High-Performance Flexible Biosensors

Yanbing Yang et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

Review Biotechnology & Applied Microbiology

Aptamers as targeted therapeutics: current potential and challenges

Jiehua Zhou et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Biochemistry & Molecular Biology

Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine

Zhenjian Zhuo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemical Research Methods

Selection of aptamers based on a protein microarray integrated with a microfluidic chip

Xiaohui Liu et al.

LAB ON A CHIP (2017)

Article Chemistry, Analytical

Selection of DNA aptamers against penicillin G using Capture-SELEX for the development of an impedimetric sensor

Nathalie Paniel Georges Istamboulie et al.

TALANTA (2017)

Article Medicine, Research & Experimental

A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect

Bo-Tsang Huang et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2017)

Article Microbiology

An Aptamer-Based Biosensor for the Azole Class of Antifungal Drugs

Gregory R. Wiedman et al.

MSPHERE (2017)

Article Multidisciplinary Sciences

Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors

Iman Jeddi et al.

SCIENTIFIC REPORTS (2017)

Article Biochemical Research Methods

High affinity truncated DNA aptamers for the development of fluorescence based progesterone biosensors

Hani Alhadrami et al.

ANALYTICAL BIOCHEMISTRY (2017)

Article Chemistry, Medicinal

DNA-duplex linker for AFM-SELEX of DNA aptamer against human serum albumin

Musashi Takenaka et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Nanoscience & Nanotechnology

Selective Fluorogenic Sensing of As(III) Using Aptamer-Capped Nanomaterials

Mar Oroval et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Review Chemistry, Analytical

Aptamers: versatile molecular recognition probes for cancer detection

Hongguang Sun et al.

ANALYST (2016)

Article Biophysics

Label-free signal-on aptasensor for sensitive electrochemical detection of arsenite

Lin Cui et al.

BIOSENSORS & BIOELECTRONICS (2016)

Article Biochemistry & Molecular Biology

Aromatic Surfactant as Aggregating Agent for Aptamer-Gold Nanoparticle-Based Detection of Plasmodium Lactate Dehydrogenase

Priyamvada Jain et al.

MOLECULAR BIOTECHNOLOGY (2016)

Article Radiology, Nuclear Medicine & Medical Imaging

Aptamers as radiopharmaceuticals for nuclear imaging and therapy

Marlies Gijs et al.

NUCLEAR MEDICINE AND BIOLOGY (2016)

Article Medicine, Research & Experimental

E-selectin Targeting PEGylated-thioaptamer Prevents Breast Cancer Metastases

Yoshihiro Morita et al.

Molecular Therapy-Nucleic Acids (2016)

Article Medicine, Research & Experimental

Targeting Insulin Receptor with a Novel Internalizing Aptamer

Margherita Iaboni et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2016)

Article Multidisciplinary Sciences

A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly

Maia Godonoga et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

Acousto-microfluidics for screening of ssDNA aptamer

Jee-Woong Park et al.

SCIENTIFIC REPORTS (2016)

Article Chemistry, Multidisciplinary

APTEC: aptamer-tethered enzyme capture as a novel rapid diagnostic test for malaria

Roderick M. Dirkzwager et al.

CHEMICAL COMMUNICATIONS (2015)

Article Clinical Neurology

Postoperative hemicrania continua-like headache - a case series

Andreas R. Gantenbein et al.

JOURNAL OF HEADACHE AND PAIN (2015)

Article Multidisciplinary Sciences

Detection of Cryptosporidium parvum Oocysts on Fresh Produce Using DNA Aptamers

Asma Iqbal et al.

PLOS ONE (2015)

Article Multidisciplinary Sciences

Screening and Identifying a Novel ssDNA Aptamer against Alpha-fetoprotein Using CE-SELEX

Lili Dong et al.

SCIENTIFIC REPORTS (2015)

Review Chemistry, Analytical

Aptamer-based biosensors for biomedical diagnostics

Wenhu Zhou et al.

ANALYST (2014)

Review Biochemistry & Molecular Biology

Directed polymerase evolution

Tingjian Chen et al.

FEBS LETTERS (2014)

Article Biochemistry & Molecular Biology

Identification of DNA Aptamers toward Epithelial Cell Adhesion Molecule via Cell-SELEX

Ji Won Kim et al.

MOLECULES AND CELLS (2014)

Article Multidisciplinary Sciences

DNA Aptamer Evolved by Cell-SELEX for Recognition of Prostate Cancer

Yuanyuan Wang et al.

PLOS ONE (2014)

Article Multidisciplinary Sciences

In vitro selection with artificial expanded genetic information systems

Kwame Sefah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Chemistry, Analytical

DNA-Aptamers Binding Aminoglycoside Antibiotics

Nadia Nikolaus et al.

SENSORS (2014)

Article Biochemistry & Molecular Biology

DNA-Aptamer Targeting Vimentin for Tumor Therapy In Vivo

Tatyana N. Zamay et al.

NUCLEIC ACID THERAPEUTICS (2014)

Article Infectious Diseases

Aptamer Based, Non-PCR, Non-Serological Detection of Chagas Disease Biomarkers in Trypanosoma cruzi Infected Mice

Rana Nagarkatti et al.

PLOS NEGLECTED TROPICAL DISEASES (2014)

Article Allergy

A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders

Chuang-Wei Wang et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Article Biotechnology & Applied Microbiology

Generation of high-affinity DNA aptamers using an expanded genetic alphabet

Michiko Kimoto et al.

NATURE BIOTECHNOLOGY (2013)

Article Medicine, General & Internal

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease

William J. Sandborn et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Biochemistry & Molecular Biology

In Vitro Selection of Modified RNA Aptamers Against CD44 Cancer Stem Cell Marker

Nidaa Ababneh et al.

NUCLEIC ACID THERAPEUTICS (2013)

Article Medicine, Research & Experimental

In vivo SELEX for Identification of Brain-penetrating Aptamers

Congsheng Cheng et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2013)

Article Biochemical Research Methods

Harnessing aptamers for electrochemical detection of endotoxin

Sung-Eun Kim et al.

ANALYTICAL BIOCHEMISTRY (2012)

Article Chemistry, Analytical

Aptamer-Based Viability Impedimetric Sensor for Viruses

Mahmoud Labib et al.

ANALYTICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Selection of RNA aptamers against mouse embryonic stem cells

Toshiro Iwagawa et al.

BIOCHIMIE (2012)

Article Chemistry, Medicinal

A Novel Aptamer Developed for Breast Cancer Cell Internalization

Kejing Zhang et al.

CHEMMEDCHEM (2012)

Article Agriculture, Multidisciplinary

Selection and Identification of a DNA Aptamer Targeted to Vibrio parahemolyticus

Nuo Duan et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

5′-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity

Sun-Young Hwang et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biochemistry & Molecular Biology

Development of Single-Stranded DNA Aptamers for Specific Bisphenol A Detection

Minjoung Jo et al.

OLIGONUCLEOTIDES (2011)

Article Multidisciplinary Sciences

Probing the Limits of Aptamer Affinity with a Microfluidic SELEX Platform

Kareem M. Ahmad et al.

PLOS ONE (2011)

Article Biotechnology & Applied Microbiology

Selection and characterization of DNA aptamers with binding selectivity to Campylobacter jejuni using whole-cell SELEX

Hari P. Dwivedi et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Electrochemical aptasensor for tetracycline detection

Yoon-Jin Kim et al.

BIOPROCESS AND BIOSYSTEMS ENGINEERING (2010)

Article Biochemical Research Methods

A Novel Screening Method for Competitive FRET-Aptamers Applied to E. coli Assay Development

John G. Bruno et al.

JOURNAL OF FLUORESCENCE (2010)

Article Biochemistry & Molecular Biology

Reprogramming bacteria to seek and destroy an herbicide

Joy Sinha et al.

NATURE CHEMICAL BIOLOGY (2010)

Article Biochemical Research Methods

Development of DNA aptamers using Cell-SELEX

Kwame Sefah et al.

NATURE PROTOCOLS (2010)

Article Biochemical Research Methods

Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures

Guenter Mayer et al.

NATURE PROTOCOLS (2010)

Article Biochemistry & Molecular Biology

Selection of DNA aptamers using atomic force microscopy

Yusuke Miyachi et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Multidisciplinary Sciences

Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing

Minseon Cho et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Engineering, Environmental

Arsenic Removal from Vietnamese Groundwater Using the Arsenic-Binding DNA Aptamer

Mina Kim et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2009)

Review Pathology

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

Paula J. Bates et al.

EXPERIMENTAL AND MOLECULAR PATHOLOGY (2009)

Article Biochemical Research Methods

Plastic-Adherent DNA Aptamer-Magnetic Bead and Quantum Dot Sandwich Assay for Campylobacter Detection

John G. Bruno et al.

JOURNAL OF FLUORESCENCE (2009)

Article Pharmacology & Pharmacy

Anti-Ccl2 Spiegelmer Permits 75% Dose Reduction of Cyclophosphamide to Control Diffuse Proliferative Lupus Nephritis and Pneumonitis in MRL-Fas(lpr) Mice

Onkar Kulkarni et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Review Hematology

The molecular mechanisms of immunomodulation and tolerance induction to factor VIII

B. Waters et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2009)

Article Biochemistry & Molecular Biology

Combining use of a panel of ssDNA aptamers in the detection of Staphylococcus aureus

Xiaoxiao Cao et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

Micromagnetic selection of aptamers in microfluidic channels

Xinhui Lou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Chemistry, Analytical

Selection of aptamers against live bacterial cells

Camille L. A. Hamula et al.

ANALYTICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Isolation of inhibitory RNA aptamers against severe acute respiratory syndrome (SARS) coronavirus NTPase/Helicase

Kyoung Jin Jang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Article Agriculture, Multidisciplinary

Determination of Ochratoxin A with a DNA Aptamer

Jorge A. Cruz-Aguado et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)

Review Oncology

Paul Ehrlich's magic bullet concept: 100 years of progress

Klaus Strebhardt et al.

NATURE REVIEWS CANCER (2008)

Article Urology & Nephrology

Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice

Onkar Kulkarni et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

Article Biochemistry & Molecular Biology

Aptamer from whole-bacterium SELEX as new therapeutic reagent against virulent Mycobacterium tuberculosis

Fan Chen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Biotechnology & Applied Microbiology

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

EWM Ng et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Chemistry, Multidisciplinary

In vitro selection of aptamers with affinity for neuropeptide Y using capillary electrophoresis

SD Mendonsa et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Chemistry, Multidisciplinary

In vitro selection of structure-switching signaling aptamers

R Nutiu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)

Article Chemistry, Multidisciplinary

In vitro evolution of functional DNA using capillary electrophoresis

SD Mendonsa et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Medicine, General & Internal

Pegaptanib for neovascular age-related macular degeneration

ES Gragoudas et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Immunology

Complement activation determines the therapeutic activity of rituximab in vivo

N Di Gaetano et al.

JOURNAL OF IMMUNOLOGY (2003)

Article Biochemistry & Molecular Biology

Inhibition of HCVNS3 protease by RNA aptamers in cells

F Nishikawa et al.

NUCLEIC ACIDS RESEARCH (2003)

Article Multidisciplinary Sciences

RNA aptamers as reversible antagonists of coagulation factor IXa

CP Rusconi et al.

NATURE (2002)