期刊
MOLECULES
卷 24, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/molecules24030476
关键词
anti-inflammatory; Laurencia obtusa; acetogenins; spectroscopy; Red Sea
资金
- Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah [G-364-150-39]
- DSR
Three new rare C-12 acetogenins (enyne derivatives 1-3) were isolated from the organic extract obtained from the red alga Laurencia obtusa, collected from the Red Sea. The chemical structures of the isolated compounds were established by spectroscopical data analyses. Potent anti-inflammatory effect of the isolated metabolites was evidenced by inhibition of the release of inflammatory mediators (e.g., TNF-alpha, IL-1 beta and IL-6) by employing Human Peripheral Blood Mononuclear Cells (PBMC).
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