期刊
MICROBIAL PATHOGENESIS
卷 128, 期 -, 页码 178-183出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micpath.2019.01.003
关键词
Janthinobacterium sp.; Complete genome sequencing; Violacein; Antibiotic
资金
- National Natural Science Foundation of China [21776136, 21606129, U1603112]
- Program for Innovative Research Teams in Universities of Jiangsu Province
- Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture [XTC1810]
Janthinobacterium sp. B9-8, isolated from low temperature-sewage in Xinjiang, China, is capable of producing violacein, a promising antibiotic. Here we report the genome sequence of B9-8, which consist of 4,726,850 bp with a G + C content of 48.72%. The violacein biosynthesis gene cluster vioABCDE was identified and analyzed based on the genomic data, which revealed relatively low query coverage (3-44%) and identity (66-87%) with existing strains. Janthinobacterium sp. B9-8 grew fast and reached a high cell density and violacein content within 24 h at 25 degrees C. The availability of this genome sequence will greatly benefit the industrial production of violacein and facilitate supplementary studies on the mechanism for violacein biosynthesis.
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