期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 408, 期 11, 页码 2687-2695出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-015-9251-8
关键词
Laser ablation; ICPMS; Elemental imaging; Mass spectrometry; Time-of-flight
资金
- Marie Curie International Incoming Fellowship from European Union Seventh Framework Programme [624280]
We describe trends in fast, high resolution elemental imaging by laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS). Recently developed low dispersion LA cells deliver quantitative transport of ablated aerosols within 10 ms and also provide enhanced sensitivity compared to conventional LA cells because the analyte ion signal becomes less diluted during aerosol transport. When connected to simultaneous ICPMS instruments, these low dispersion LA cells offer a platform for high speed and high lateral resolution shot-resolved LA-ICPMS imaging. Here, we examine the current paradigms of LA-ICPMS imaging and discuss how newly developed LA cell technology combined with simultaneous ICPMS instrumentation is poised to overcome current instrumental limitations to deliver faster, higher resolution elemental imaging.
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