In vitro cytotoxicity studies of surface modified CaS nanoparticles on L929 cell lines using MTT assay

Recently, CaS nanoparticles have attracted great interest because of their use in various biomedical applications. The nanoparticles should be biocompatible for its application in the biomedical field. We synthesized highly luminescent CaS nanoparticles capped with Triethanolamine (TEOA) using wet chemical coprecipitation method and its structural and optical characterization were done. The cytotoxicity analysis was carried out in human fibroblast cell lines using MIT assay, and cell imaging was done using an inverted phase contrast tissue culture microscope. The percentage viability of the samples was compared with control and the IC50 value of the nanoparticles was calculated. (C) 2018 Elsevier B.V. All rights reserved.