期刊
MARINE DRUGS
卷 17, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/md17020120
关键词
Briareum violaceum; briarenones; briarellin; gorgonian
资金
- Ministry of Science and Technology of Taiwan [MOST104-2113-M-110-006, 104-2811-M-110-026]
- International Scientific Partnership Program (ISPP) at King Saud University, Saudi Arabia [ISPP-116]
Three new eunicellin-derived diterpenoids of briarellin type, briarenones AC (13), were isolated from a Formosan gorgonian Briareum violaceum. The chemical structures of the compounds were elucidated on the basis of extensive spectroscopic analyses, including two-dimensional (2D) NMR. The absolute configuration of 1 was further confirmed by a single crystal X-ray diffraction analysis. The in vitro cytotoxic and anti-inflammatory potentialities of the isolated metabolites were tested against the growth of a limited panel of cancer cell lines and against the production of superoxide anions and elastase release in N-formyl-methionyl-leucyl-phenyl-alanine and cytochalasin B (fMLF/CB)-stimulated human neutrophils, respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据