期刊
LASERS IN MEDICAL SCIENCE
卷 34, 期 9, 页码 1791-1797出版社
SPRINGER LONDON LTD
DOI: 10.1007/s10103-019-02775-8
关键词
Linked color imaging; Gastric intestinal metaplasia; White light endoscopy; Detection; Diagnosis
资金
- Guangzhou Science and Technology Project [201803010040]
- Guangdong Province Science and Technology plan project [2017A010105004]
- Guangdong Province Medical Science and Technology research fund project [A2017273]
We aimed to investigate the ability of linked color imaging (LCI) versus white light endoscopy (WLE) to detect gastric intestinal metaplasia (GIM). One hundred and seven participants who underwent upper gastrointestinal endoscopy were included. Under WLE endoscopy, biopsies were performed on any suspected abnormal mucosal changes. Under LCI endoscopy, we tested whether the specific color feature of patchy lavender color (PLC) pathologically indicated GIM. Biopsies were randomly performed in participants who had neither PLC nor suspected lesions. The detection abilities of LCI and WLE were assessed by comparison of histological and endoscopic findings. A total of 41 participants had histological GIM. The total diagnostic accuracy rate for GIM by LCI was 79.44%, higher than that of WLE (40.19%) (P<0.001). Moreover, LCI with targeted biopsies showed a significantly increased ability to detect GIM (P<0.001). PLC observed in the gastric mucosa on LCI can guide endoscopic biopsies and increase the detection rate of GIM. Thus, LCI could be a good tool for detecting GIM. ClinicalTrials.gov Identifier: ChiCTR-DDD-17011326)
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