期刊
ANALYTICA CHIMICA ACTA
卷 925, 期 -, 页码 70-81出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2016.04.030
关键词
Interdigitated electrode; ZnO nanowire; Glucose; Biosensor; Sol-gel
资金
- Institute of Nano Electronic Engineering (INEE), University Malaysia Perlis (UniMAP)
- Ministry of Higher Education Malaysia through MTUN-COE [9016-00004]
Diabetes is a metabolic disease with a prolonged elevated level of glucose in the blood leads to long-term complications and increases the chances for cardiovascular diseases. The present study describes the fabrication of a ZnO nanowire (NW)-modified interdigitated electrode (IDE) to monitor the level of blood glucose. A silver IDE was generated by wet etching-assisted conventional lithography, with a gap between adjacent electrodes of 98.80 mu m. The ZnO-based thin films and NWs were amended by sol-gel and hydrothermal routes. High-quality crystalline and c-axis orientated ZnO thin films were observed by XRD analyses. The ZnO thin film was annealed for 1, 3 and 5 h, yielding a good-quality crystallite with sizes of 50, 100 and 110 nm, and the band gaps were measured as 3.26, 3.20 and 3.17 eV, respectively. Furthermore, a flower-modeled NW was obtained with the lowest diameter of 21 nm. Our designed ZnO NW-modified IDE was shown to have a detection limit as low as 0.03 mg/dL (correlation coefficient = 0.98952) of glucose with a low response time of 3 s, perform better than commercial glucose meter, suitable to instantly monitor the glucose level of diabetes patients. This study demonstrated the high performance of NW-mediated IDEs for glucose sensing as alternative to current glucose sensors. (C) 2016 Elsevier B.V. All rights reserved.
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