期刊
ANALYST
卷 141, 期 6, 页码 1906-1911出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5an02342d
关键词
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资金
- KU Leuven [IOF/KP/12/002-Nanodiag, PDM/15/111]
- IWT-Sensors for Food [100936]
- IWT-LA [110770]
A fiber optic surface plasmon resonance (FO-SPR) technology was developed that enables simultaneous quantification and identification of multiple DNA targets on the same platform. The bioassay was based on the hybridization/melting of DNA-coated Au nano-particles on the FO-SPR sensor when targets are present. The multiplex concept was successfully demonstrated on two related bacteria and for detection of multiple mutations in sequences. In conclusion, FO-SPR technology shows a great potential as a next generation in vitro diagnostics tool.
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