期刊
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
卷 20, 期 5, 页码 634-+出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jamda.2018.12.012
关键词
Frailty; exercise; sedentary lifestyle; aging; public health; epidemiology
资金
- Biomedical Research Networking Center on Frailty and Healthy Aging (CIBERFES)
- FEDER funds from the European Union [CB16/10/00477, CB16/10/00456]
- Government of Castilla-La Mancha [PI2010/020]
- Government of Castilla-La Mancha (Institute of Health Sciences, Ministry of Health of Castilla-La Mancha) [03031-00]
- Spanish Government (Spanish Ministry of Economy, Ministerio de Economia y Competitividad, Instituto de Salud Carlos III) [PI10/01532, PI031558, PI11/01068]
- European Grants (Seventh Framework Programme: FRAILOMIC)
- Universidad de Castilla-La Mancha Contratos predoctorales para la formacion de personal investigador en el marco del Plan Propio de I thorn D thorn i, cofinanciados por el Fondo Social Europeo [2015/4062, 2014/10340]
Objectives: To determine whether or not and to what extent the association between sedentary time and frailty was moderated by moderate-to-vigorous physical activity in older adults. Design: Cross-sectional. Setting: Community-dwelling individuals. Participants: 749 (403 females and 346 males) white older adults. Measurements: Sedentary time and moderate-to-vigorous physical activity were measured with accelerometers. Frailty was objectively measured using the Frailty Trait Scale. All models were adjusted for age, sex, education, income, marital status, body mass index, moderate-to-vigorous physical activity, and accelerometer wear time. Results: The regression model reported a significant effect of sedentary time on frailty (P<.05). Nevertheless, the results indicated that moderate-to-vigorous physical activity moderates the relationship between frailty status and sedentary time. The Johnson-Neyman technique determined that the estimated moderate-to-vigorous physical activity point was 27.25 minutes/d, from which sedentary time has no significant effect on frailty. Conclusions: Moderate-to-vigorous physical activity is a moderator in the relationship between sedentary time and frailty in older adults, offsetting the harmful effects of sedentary behavior with 27 minutes/d of moderate-to-vigorous activity. Engaging in moderate-to-vigorous physical activities should be encouraged. Reducing sedentary behavior may also be beneficial, particularly among inactive older adults. (C) 2018 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
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