The enhanced photo-thermal therapy of Surface improved photoactive cadmium sulfide (CdS) quantum dots entrenched graphene oxide nanoflakes in tumor treatment

Cancer is one of the death causing disease is always being a public health concern due to its rapid increase in the world population. Hyperthermal therapy is an anticancer treatment mutually given with chemotherapy. In the present study, CdS/rGO nanocomposites were synthesized using simple and scalable solvothermal method and applied as an efficient material in anticancer treatment. The prepared nanocomposites were characterized from physicochemical characterization techniques. The surface morphology and the crystallographic details were obtained from TEM and XRD analyses respectively. The elemental composition was confirmed from XPS spectra. The phase purity and the functional group analysis were done using Raman and FTIR spectroscopies respectively. The morphological analysis has been displayed the spherical shaped CdS nanoparticles that are firmly attached on the rGO thin sheet matrix further confirmed the formation of CdS/rGO nanoflakes. The live-dead assay method (cancerous and normal cell lines) cytocompatibility study displayed the cell survival of the CdS/rGO nanomaterials exhibited that above 95%, which means materials highly appropriate for the cancer therapy. The temperature profile of the CdS/rGO nanoflakes has enhanced effectively under the NIR absorption property of CdS coated rGO nanoflakes, which influenced to the cancer cell death. The results shown the anticancer activity of the proposed nanocomposites could open a new avenue in biomedicine research and utilized as an efficient materials for practical applications.