期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 84, 期 7, 页码 3754-3761出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b00095
关键词
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资金
- Simons Foundation [290363]
The ability of the biopolymers RNA and DNA to store and transfer information is essential to life. Herein, we demonstrate template-directed replication in a set of dimer duplexes that use reversible covalent bonds to form base-pairing interactions. Binary sequence information was encoded as a sequence of aniline and benzaldehyde subunits linked together by a diethynyl benzene backbone. These dimers formed sequence-specific, imine-linked duplexes, which could be separated and used as templates for the synthesis of daughter duplexes with identical sequences.
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