期刊
JOURNAL OF HAZARDOUS MATERIALS
卷 366, 期 -, 页码 329-337出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jhazmat.2018.12.004
关键词
Biosorption; Metabonomics; Benzo(a)pyrene; Phospholipid; Metabolism pathway
资金
- National Natural Science Foundation of China [21577049, 41501352]
- Science and Technology Project of Guangzhou City [201707010255]
The relationship between benzo(a)pyrene biodegradation and certain target biomolecules has been investigated. To regulate the degradation process, the associated metabolism network must be clarified. To this end, benzo(a) pyrene degradation, carbon substrate metabolism and exometabolomic mechanism of Bacillus thuringiensis were analyzed. Benzo(a)pyrene was degraded through hydroxylation catalyzed by cytochrome P450 hydroxylase. After the treatment of 0.5 mg L-1 of benzo(a)pyrene by 0.2 g L-1 of cells for 9 d, biosorption and degradation efficiencies were measured at approximately 90% and 80%, respectively. During this process, phospholipid synthesis, glycogen, asparagine, arginine, itaconate and xylose metabolism were significantly downregulated, while glycolysis, pentose phosphate pathway, citrate cycle, amino sugar and nucleotide sugar metabolism were significantly upregulated. These findings offer insight into the biotransformation regulation of polycyclic aromatic hydrocarbons.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据