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microRNAs: New prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

期刊

JOURNAL OF CELLULAR PHYSIOLOGY
卷 234, 期 10, 页码 17064-17099

出版社

WILEY
DOI: 10.1002/jcp.28457

关键词

cervical cancer; diagnosis; exosome; Human papillomavirus; microRNA; therapy

资金

  1. Kashan University of Medical Sciences (KAUMS) [125465]

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Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer could be observed in women who infected with papillomavirus, regular oral contraceptives, and multiple pregnancies. Early detection of cervical cancer is one of the most important aspects of the therapy of this malignancy. Despite several efforts, finding and developing new biomarkers for cervical cancer diagnosis are required. Among various prognostic, diagnostic, and therapeutic biomarkers, miRNA have been emerged as powerful biomarkers for detection, treatment, and monitoring of response to therapy in cervical cancer. Here, we summarized various miRNAs as an employable platform for prognostic, diagnostic, and therapeutic biomarkers in the treatment of cervical cancer.

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