相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。WITHDRAWN-a resource for withdrawn and discontinued drugs
Vishal B. Siramshetty et al.
NUCLEIC ACIDS RESEARCH (2016)
Mutagenic and carcinogenic structural alerts and their mechanisms of action
Alja Plosnik et al.
ARHIV ZA HIGIJENU RADA I TOKSIKOLOGIJU-ARCHIVES OF INDUSTRIAL HYGIENE AND TOXICOLOGY (2016)
Phase II and phase III failures: 2013-2015
Richard K. Harrison
NATURE REVIEWS DRUG DISCOVERY (2016)
QSAR modeling for predicting reproductive toxicity of chemicals in rats for regulatory purposes
Nikita Basant et al.
TOXICOLOGY RESEARCH (2016)
Deleterious effects of benomyl and carbendazim on human placental trophoblast cells
Jinghua Zhou et al.
REPRODUCTIVE TOXICOLOGY (2015)
An unusual side effect of isotretinoin: retinoid dermatitis affecting external urethral meatus
Nuran Alli et al.
CUTANEOUS AND OCULAR TOXICOLOGY (2015)
ADReCS: an ontology database for aiding standardization and hierarchical classification of adverse drug reaction terms
Mei-Chun Cai et al.
NUCLEIC ACIDS RESEARCH (2015)
Exploratory toxicology as an integrated part of drug discovery. Part I: Why and how
Jorrit J. Hornberg et al.
DRUG DISCOVERY TODAY (2014)
Computational models to predict endocrine-disrupting chemical binding with androgen or oestrogen receptors
Yingjie Chen et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2014)
Mechanism of Inhibition of Estrogen Biosynthesis by Azole Fungicides
Chinaza Egbuta et al.
ENDOCRINOLOGY (2014)
Assessing the genotoxicities of sparteine and compounds isolated from Lupinus mexicanus and L. montanus seeds by using comet assay
M. R. Silva et al.
GENETICS AND MOLECULAR RESEARCH (2014)
QSAR Modeling: Where Have You Been? Where Are You Going To?
Artem Cherkasov et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices
J. Craig Rowlands et al.
TOXICOLOGICAL SCIENCES (2014)
Exposure to diethylstilbestrol during sensitive life stages: A legacy of heritable health effects
Casey E. Reed et al.
BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2013)
Occupational Exposure to Organophosphate and Carbamate Pesticides Affects Sperm Chromatin Integrity and Reproductive Hormone Levels among Venezuelan Farm Workers
Leticia Miranda-Contreras et al.
JOURNAL OF OCCUPATIONAL HEALTH (2013)
Piperidine alkaloids: Human and food animal teratogens
Benedict T. Green et al.
FOOD AND CHEMICAL TOXICOLOGY (2012)
In Silico Assessment of Chemical Biodegradability
Feixiong Cheng et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
In silico Prediction of Chemical Ames Mutagenicity
Congying Xu et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
Predictive Model of Rat Reproductive Toxicity from ToxCast High Throughput Screening
Matthew T. Martin et al.
BIOLOGY OF REPRODUCTION (2011)
Xenobiotic Effects on Ovarian Preantral Follicles
Connie J. Mark-Kappeler et al.
BIOLOGY OF REPRODUCTION (2011)
PaDEL-Descriptor: An Open Source Software to Calculate Molecular Descriptors and Fingerprints
Chun Wei Yap
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
Thalidomide: The Tragedy of Birth Defects and the Effective Treatment of Disease
James H. Kim et al.
TOXICOLOGICAL SCIENCES (2011)
LIBSVM: A Library for Support Vector Machines
Chih-Chung Chang et al.
ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY (2011)
A machine learning approach to predicting protein-ligand binding affinity with applications to molecular docking
Pedro J. Ballester et al.
BIOINFORMATICS (2010)
Molecular aspects of azoles-induced teratogenesis
Francesca Marotta et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2010)
Estimation of ADME Properties with Substructure Pattern Recognition
Jie Shen et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Hybrid-genetic algorithm based descriptor optimization and QSAR models for predicting the biological activity of Tipranavir analogs for HIV protease inhibition
A. Srinivas Reddy et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2010)
Analytical Performance Issues - GESTIS Database: International Limit Values for Chemical Agents - A Readily accessible Source of Occupational Exposure Limits (OELs)
Dietmar Breuer
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE (2010)
QSAR classification of estrogen receptor binders and pre-screening of potential pleiotropic EDCs
J. Li et al.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH (2010)
Thalidomide-induced limb defects: resolving a 50-year-old puzzle
Neil Vargesson
BIOESSAYS (2009)
QSAR models for reproductive toxicity and endocrine disruption in regulatory use - a preliminary investigation
G. E. Jensen et al.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH (2008)
A comprehensive model for reproductive and developmental toxicity hazard identification: II. Construction of QSAR models to predict activities of untested chemicals
Edwin J. Matthews et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2007)
In silico prediction of cytochrome P450 2D6 and 3A4 inhibition using Gaussian kernel weighted k-nearest neighbor and extended connectivity fingerprints, including structural fragment analysis of inhibitors versus noninhibitors
Berith F. Jensen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Structure-based modelling in reproductive toxicology: (Q)SARs for the placental barrier
M. Hewitt et al.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH (2007)
Maternal occupational exposure and risk of specific birth defects
Ane Marie Thulstrup et al.
OCCUPATIONAL MEDICINE-OXFORD (2006)
The influence of occupational exposure on male reproductive function
Tina Kold Jensen et al.
OCCUPATIONAL MEDICINE-OXFORD (2006)
A naive Bayes classifier for prediction of multidrug resistance reversal activity on the basis of atom typing
HM Sun
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Occupational exposure associated with reproductive dysfunction
S Kumar
JOURNAL OF OCCUPATIONAL HEALTH (2004)
Effect of occupational exposures on male fertility: Literature review
EK Sheiner et al.
INDUSTRIAL HEALTH (2003)
Pyridines in cigarette smoke inhibit hamster oviductal functioning in picomolar doses
K Riveles et al.
REPRODUCTIVE TOXICOLOGY (2003)
Random forest: A classification and regression tool for compound classification and QSAR modeling
V Svetnik et al.
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2003)
2,4,6-trinitrotoluene-induced reproductive toxicity via oxidative DNA damage by its metabolite
S Homma-Takeda et al.
FREE RADICAL RESEARCH (2002)
Review of recent epidemiological studies on paternal occupations and birth defects
SE Chia et al.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2002)
QSAR and k-nearest neighbor classification analysis of selective cyclooxygenase-2 inhibitors using topologically-based numerical descriptors
GW Kauffman et al.
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2001)
Artificial neural networks: fundamentals, computing, design, and application
IA Basheer et al.
JOURNAL OF MICROBIOLOGICAL METHODS (2000)