期刊
JOURNAL OF ALZHEIMERS DISEASE
卷 68, 期 1, 页码 197-203出版社
IOS PRESS
DOI: 10.3233/JAD-180959
关键词
Aging; Asians; cross-sectional analysis; mild cognitive impairment; mushrooms
资金
- National University of Singapore Virtual Institute for the Study of Ageing [VG-8]
- Alice Lim Memorial Fund, Singapore [ALMFA/2010]
- National Medical Research Council of Singapore [NMRC/TA/0053/2016, NMRC/1264/2010/082/12]
- Training and Research Academy at Jurong Point, Singapore
- Lee Kim Tah Holdings Ltd., Singapore
- Kwan Im Thong Hood Cho Temple, Singapore
- Presbyterian Community Services, Singapore
We examined the cross-sectional association between mushroom intake and mild cognitive impairment (MCI) using data from 663 participants aged 60 and above from the Diet and Healthy Aging (DaHA) study in Singapore. Compared with participants who consumed mushrooms less than once per week, participants who consumed mushrooms >2 portions per week had reduced odds of having MCI (odds ratio = 0.43, 95% CI 0.23-0.78, p = 0.006) and this association was independent of age, gender, education, cigarette smoking, alcohol consumption, hypertension, diabetes, heart disease, stroke, physical activities, and social activities. Our cross-sectional data support the potential role of mushrooms and their bioactive compounds in delaying neurodegeneration.
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