期刊
AMERICAN JOURNAL OF THERAPEUTICS
卷 23, 期 2, 页码 E570-E571出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MJT.0000000000000188
关键词
hepatitis C; side effect; adverse drug reaction; direct-acting antivirals; pharmacokinetics
资金
- Gilead Sciences
Newer direct-acting antiviral agents have revolutionized the medical management of chronic hepatitis C. In addition to being extremely efficacious, they report very mild adverse drug reactions from experience in clinical trials. However, because they are relatively new on the horizon, postmarketing surveillance studies refining the safety profile are not yet available. We present a case of seizures as a potential side effect of antiviral therapy with sofosbuvir and simeprevir.
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