4.7 Review

High Risk of Hepatocellular Carcinoma Development in Fibrotic Liver: Role of the Hippo-YAP/TAZ Signaling Pathway

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Immunology

Liver-associated immune abnormalities

Eyal Grunebaum et al.

AUTOIMMUNITY REVIEWS (2019)

Review Gastroenterology & Hepatology

Relationship between Telomere Maintenance and Liver Disease

Abbey Barnard et al.

GUT AND LIVER (2019)

Review Cell Biology

Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine

Ivan M. Moya et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Article Gastroenterology & Hepatology

Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and regeneration after liver ischemia-reperfusion injury

Takanori Konishi et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2018)

Review Biochemistry & Molecular Biology

Insulin-Like Growth Factor (IGF) System in Liver Diseases

Agnieszka Adamek et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Nutrition & Dietetics

Abundance of DNA adducts of 4-oxo-2-alkenals, lipid peroxidation-derived highly reactive genotoxins

Yoshichika Kawai et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2018)

Review Medicine, Research & Experimental

Extracellular matrix as a driver of progressive fibrosis

Jeremy Herrera et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Gastroenterology & Hepatology

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

Naoto Fujiwara et al.

JOURNAL OF HEPATOLOGY (2018)

Article Gastroenterology & Hepatology

Liver regeneration requires Yap1-TGF beta-dependent epithelial-mesenchymal transition in hepatocytes

Seh-Hoon Oh et al.

JOURNAL OF HEPATOLOGY (2018)

Review Biochemistry & Molecular Biology

Targeting Gas6/TAM in cancer cells and tumor microenvironment

Guiling Wu et al.

MOLECULAR CANCER (2018)

Article Biochemistry & Molecular Biology

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors

Thijs J. Hagenbeek et al.

SCIENCE SIGNALING (2018)

Review Biochemistry & Molecular Biology

Dynamics of Axl Receptor Shedding in Hepatocellular Carcinoma and Its Implication for Theranostics

Elisa Holstein et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Editorial Material Respiratory System

TGF-β: Master regulator of inflammation and fibrosis

Alastair G. Stewart et al.

RESPIROLOGY (2018)

Article Multidisciplinary Sciences

NUAK2 is a critical YAP target in liver cancer

Wei-Chien Yuan et al.

NATURE COMMUNICATIONS (2018)

Review Oncology

Update in global trends and aetiology of hepatocellular carcinoma

Prashanth Rawla et al.

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY (2018)

Article Medicine, Research & Experimental

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2

Giulio Loforese et al.

EMBO MOLECULAR MEDICINE (2017)

Article Oncology

Modulation of hepatic stellate cells and reversibility of hepatic fibrosis

Yu Huang et al.

EXPERIMENTAL CELL RESEARCH (2017)

Article Gastroenterology & Hepatology

Transforming Growth Factor-β Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail

Hyuk Moon et al.

GASTROENTEROLOGY (2017)

Review Biochemistry & Molecular Biology

The Role of Growth Hormone and Insulin-Like Growth Factor-I in the Liver

Yutaka Takahashi

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Oncology

PDGF signaling pathway in hepatic fibrosis pathogenesis and therapeutics

Hua-Zhong Ying et al.

MOLECULAR MEDICINE REPORTS (2017)

Review Cell Biology

Mechanobiology of YAP and TAZ in physiology and disease

Tito Panciera et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Gastroenterology & Hepatology

Implication of the Hedgehog pathway in hepatocellular carcinoma

Carminia Maria Della Corte et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2017)

Review Cell Biology

Molecular insights of Gas6/TAM in cancer development and therapy

Guiling Wu et al.

CELL DEATH & DISEASE (2017)

Article Multidisciplinary Sciences

YAP determines the cell fate of injured mouse hepatocytes in vivo

Norio Miyamura et al.

NATURE COMMUNICATIONS (2017)

Review Anatomy & Morphology

The stellate cell system (vitamin A-storing cell system)

Haruki Senoo et al.

ANATOMICAL SCIENCE INTERNATIONAL (2017)

Review Immunology

Production of complement components by cells of the immune system

R. Lubbers et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2017)

Article Multidisciplinary Sciences

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

Miki Nishio et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Gastroenterology & Hepatology

TAM receptor tyrosine kinase function and the immunopathology of liver disease

S. K. Mukherjee et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2016)

Article Medicine, Research & Experimental

Gas6 as a putative noninvasive biomarker of hepatic fibrosis

Mattia Bellan et al.

BIOMARKERS IN MEDICINE (2016)

Article Gastroenterology & Hepatology

Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background

Sook In Chung et al.

BMC GASTROENTEROLOGY (2016)

Review Oncology

YAP/TAZ at the Roots of Cancer

Francesca Zanconato et al.

CANCER CELL (2016)

Review Immunology

Liver immunology and its role in inflammation and homeostasis

Mark W. Robinson et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2016)

Review Cell Biology

Mechanisms of Hippo pathway regulation

Zhipeng Meng et al.

GENES & DEVELOPMENT (2016)

Review Immunology

Innate immune mediators in cancer: between defense and resistance

Pedro Berraondo et al.

IMMUNOLOGICAL REVIEWS (2016)

Review Gastroenterology & Hepatology

IL-6 pathway in the liver: From physiopathology to therapy

Dirk Schmidt-Arras et al.

JOURNAL OF HEPATOLOGY (2016)

Review Urology & Nephrology

TGF-β: the master regulator of fibrosis

Xiao-ming Meng et al.

NATURE REVIEWS NEPHROLOGY (2016)

Review Biochemical Research Methods

Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine

Wieland Schroedl et al.

PROTEOMICS CLINICAL APPLICATIONS (2016)

Article Cell Biology

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

Fuqin Fan et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Review Cell Biology

ROS homeostasis and metabolism: a dangerous liason in cancer cells

E. Panieri et al.

CELL DEATH & DISEASE (2016)

Article Medicine, General & Internal

Hepatocellular carcinoma

Josep M. Llovet et al.

NATURE REVIEWS DISEASE PRIMERS (2016)

Article Multidisciplinary Sciences

Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution

Andrea Baiocchini et al.

PLOS ONE (2016)

Article Multidisciplinary Sciences

IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner

Hitoshi Nishizawa et al.

SCIENTIFIC REPORTS (2016)

Review Gastroenterology & Hepatology

Hepatic Inflammation and Fibrosis: Functional Links and Key Pathways

Ekihiro Seki et al.

HEPATOLOGY (2015)

Article Gastroenterology & Hepatology

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Inge Mannaerts et al.

JOURNAL OF HEPATOLOGY (2015)

Editorial Material Multidisciplinary Sciences

Understanding the origins of human cancer

Ludmil B. Alexandrov

SCIENCE (2015)

Review Gastroenterology & Hepatology

Reversibility of liver fibrosis

Mengxi Sun et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2015)

Review Biochemistry & Molecular Biology

Cross-talk between Wnt/β-catenin and Hippo signaling pathways: a brief review

Minseong Kim et al.

BMB REPORTS (2014)

Article Biochemistry & Molecular Biology

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

Luca Azzolin et al.

Article Gastroenterology & Hepatology

Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance

Tom Luedde et al.

GASTROENTEROLOGY (2014)

Review Biotechnology & Applied Microbiology

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

Randy Johnson et al.

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Multidisciplinary Sciences

Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis

Hayato Nakagawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Gastroenterology & Hepatology

Pathogenesis of liver cirrhosis

Wen-Ce Zhou et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Gastroenterology & Hepatology

Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update

Gulsum Ozlem Elpek

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Immunology

Expression and Clinical Significance of YAP, TAZ, and AREG in Hepatocellular Carcinoma

Su-xia Han et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2014)

Review Oncology

Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?

Simran S. Sabharwal et al.

NATURE REVIEWS CANCER (2014)

Review Oncology

STAT3 in hepatocellular carcinoma: new perspectives

Jasmin Svinka et al.

HEPATIC ONCOLOGY (2014)

Article Oncology

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

Qi Xie et al.

CANCER RESEARCH (2013)

Review Biochemistry & Molecular Biology

Telomerase: central regulator of all of the hallmarks of cancer

Kee Chung Low et al.

TRENDS IN BIOCHEMICAL SCIENCES (2013)

Review Biotechnology & Applied Microbiology

The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages

Daria Capece et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Review Oncology

Inflammation and liver tumorigenesis

Beicheng Sun et al.

FRONTIERS OF MEDICINE (2013)

Article Gastroenterology & Hepatology

From Cirrhosis to Hepatocellular Carcinoma: New Molecular Insights on Inflammation and Cellular Senescence

Gayatri Ramakrishna et al.

Liver Cancer (2013)

Review Oncology

The Hippo pathway and human cancer

Kieran F. Harvey et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model

Hitoshi Nishizawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Editorial Material Gastroenterology & Hepatology

Lipids in Liver Disease: Looking Beyond Steatosis

Robert F. Schwabe et al.

GASTROENTEROLOGY (2012)

Article Gastroenterology & Hepatology

Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

Yuping Chen et al.

GASTROENTEROLOGY (2012)

Article Cell Biology

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)

Jung-Soon Mo et al.

GENES & DEVELOPMENT (2012)

Article Gastroenterology & Hepatology

Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss

Shelli M. Morris et al.

HEPATOLOGY (2012)

Review Cell Biology

TGFβ signalling in context

Joan Massague

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Review Gastroenterology & Hepatology

The extracellular matrix: an active or passive player in fibrosis?

Thomas N. Wight et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)

Article Biochemistry & Molecular Biology

Silencing tissue inhibitors of metalloproteinases (TIMPs) with short interfering RNA reveals a role for TIMP-1 in hepatic stellate cell proliferation

Andrew J. Fowell et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Review Cell Biology

NF-kappa B and STAT3 - key players in liver inflammation and cancer

Guobin He et al.

CELL RESEARCH (2011)

Review Biochemistry & Molecular Biology

The role of Hedgehog signaling in fibrogenic liver repair

Steve S. Choi et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)

Review Gastroenterology & Hepatology

Hedgehog signaling in the liver

Alessia Omenetti et al.

JOURNAL OF HEPATOLOGY (2011)

Review Gastroenterology & Hepatology

NF-κB in the liver-linking injury, fibrosis and hepatocellular carcinoma

Tom Luedde et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)

Review Medicine, General & Internal

CURRENT CONCEPTS Hepatocellular Carcinoma

Hashem B. El-Serag

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Pathology

Liver Regeneration after Partial Hepatectomy Critical Analysis of Mechanistic Dilemmas

George K. Michalopoulos

AMERICAN JOURNAL OF PATHOLOGY (2010)

Review Cell Biology

The Hippo Signaling Pathway in Development and Cancer

Duojia Pan

DEVELOPMENTAL CELL (2010)

Review Biochemistry & Molecular Biology

Reactive oxygen species in cancer

Geou-Yarh Liou et al.

FREE RADICAL RESEARCH (2010)

Article Multidisciplinary Sciences

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

Hai Song et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

Li Lu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Immunology

The Liver as a Lymphoid Organ

Ian Nicholas Crispe

ANNUAL REVIEW OF IMMUNOLOGY (2009)

Article Gastroenterology & Hepatology

Blocking the Hedgehog Pathway Inhibits Hepatoblastoma Growth

Melanie Eichenmueller et al.

HEPATOLOGY (2009)

Article Biochemistry & Molecular Biology

Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo

Vladislava Juric et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Immunology

Microanatomy of the liver immune system

Eszter Nemeth et al.

SEMINARS IN IMMUNOPATHOLOGY (2009)

Article Biochemistry & Molecular Biology

SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila

Youlian Goulev et al.

CURRENT BIOLOGY (2008)

Review Cell Biology

Hedgehog Signaling in Development and Cancer

Jin Jiang et al.

DEVELOPMENTAL CELL (2008)

Review Gastroenterology & Hepatology

Mechanisms of hepatic fibrogenesis

Scott L. Friedman

GASTROENTEROLOGY (2008)

Article Virology

New diagnostic method for liver fibrosis and cirrhosis

Kwang-Hyub Han et al.

INTERVIROLOGY (2008)

Article Computer Science, Artificial Intelligence

The mechanical response of human liver and its relation to histology: An in vivo study

Edoardo Mazza et al.

MEDICAL IMAGE ANALYSIS (2007)

Article Biochemistry & Molecular Biology

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki et al.

NATURE MEDICINE (2007)

Article Biochemistry & Molecular Biology

Elucidation of a universal size-control mechanism in Drosophila and mammals

Jixin Dong et al.

Article Medicine, Research & Experimental

Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation

Alessia Omenetti et al.

LABORATORY INVESTIGATION (2007)

Article Pharmacology & Pharmacy

Dissection of Signal Transduction Pathways as a Tool for the Development of Targeted Therapies of Hepatocellular Carcinoma

Diego F. Calvisi et al.

REVIEWS ON RECENT CLINICAL TRIALS (2007)

Article Gastroenterology & Hepatology

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis

Josep M. Llovet et al.

GASTROENTEROLOGY (2006)

Review Oncology

TGFβ:: the molecular Jekyll and Hyde of cancer

Brian Bierie et al.

NATURE REVIEWS CANCER (2006)

Review Multidisciplinary Sciences

Nuclear factor-κB in cancer development and progression

Michael Karin

NATURE (2006)

Article Oncology

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

JK Sicklick et al.

CARCINOGENESIS (2006)

Article Gastroenterology & Hepatology

Mechanisms of liver injury.: I.: TNF-α-induced liver injury:: role of IKK, JNK, and ROS pathways

RF Schwabe et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)

Review Medicine, General & Internal

Biology of platelet-derived growth factor and its involvement in disease

Ricardo H. Alvarez et al.

MAYO CLINIC PROCEEDINGS (2006)

Article Oncology

Hedgehog signaling in human hepatocellular carcinoma

MA Patil et al.

CANCER BIOLOGY & THERAPY (2006)

Review Biochemistry & Molecular Biology

The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis

AM Elsharkawy et al.

APOPTOSIS (2005)

Review Cell Biology

Communicating with Hedgehogs

JE Hooper et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Multidisciplinary Sciences

Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma

JS Campbell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Oncology

The stats of cancer - New molecular targets come of age

H Yu et al.

NATURE REVIEWS CANCER (2004)

Article Multidisciplinary Sciences

NF-κB functions as a tumour promoter in inflammation-associated cancer

E Pikarsky et al.

NATURE (2004)

Review Biochemistry & Molecular Biology

Cancer genes and the pathways they control

B Vogelstein et al.

NATURE MEDICINE (2004)

Article Immunology

SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

T Yoshida et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Gastroenterology & Hepatology

Hepatocellular carcinoma in cirrhosis: Incidence and risk factors

G Fattovich et al.

GASTROENTEROLOGY (2004)

Review Oncology

Hedgehog signalling in cancer formation and maintenance

MP di Magliano et al.

NATURE REVIEWS CANCER (2003)

Article Multidisciplinary Sciences

Hexameric structure and assembly of the interleukin-6/IL-6 α-receptor/gp130 complex

MJ Boulanger et al.

SCIENCE (2003)

Review Biochemistry & Molecular Biology

Novel PDGF family members: PDGF-C and PDGF-D

XR Li et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2003)

Review Cell Biology

Mechanisms of TGF-beta-mediated apoptosis

N Schuster et al.

CELL AND TISSUE RESEARCH (2002)

Review Biochemistry & Molecular Biology

Telomerase and cancer

JW Shay et al.

HUMAN MOLECULAR GENETICS (2001)

Article Immunology

IκB kinase α is essential for mature B cell development and function

T Kaisho et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2001)

Article Biochemistry & Molecular Biology

NFκB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

F Kühnel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Review Biochemistry & Molecular Biology

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

SL Friedman

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)