期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 124, 期 -, 页码 411-417出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2018.11.214
关键词
Cellulose nanocrystals; Gelatin nanofibers; Biological properties
资金
- Iran's National Talents Foundation, Nanotechnology Innovation Council (INIC)
- Ministry of Science, Research and Technology
- NSF
Incorporation of nanoparticles into biomaterials is of interest due to the high demand for medical devices with enhanced mechanical properties. In this study, cellulose nanocrystals (CNC) were incorporated in electrospun gelatin nanofibers at various loadings (0-15% w/w) and characterized using XRD, TGA, TEM, SEM, FTIR, and tensile tests. Results obtained from TGA and tensile properties indicate that CNC were agglomerated at loadings exceeding 5%; however, TEM showed excellent dispersion of nanoparticles at 5% CNC. A slight increase in biodegradability of crosslinked gelatin nanofibers was observed with CNC incorporation. MTT cytotoxicity, fluorescent staining, and SEM images showed that CNC had no significant effect on cell growth and proliferation. (C) 2018 Published by Elsevier B.V.
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