期刊
INTERNATIONAL IMMUNOPHARMACOLOGY
卷 67, 期 -, 页码 87-97出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.intimp.2018.11.036
关键词
Multiple sclerosis; Natural products; Anti-inflammatory; Immune regulation; Neuroprotection; Nervous system repairing
资金
- National Natural Science Foundation of China [81202924, 81773909, 81703711]
- Shanghai Rising-Star Program of China [13QA1403400]
- Shanghai talent development funds [201665]
- Excellent Medical Profession Scholarship of Shanghai municipal commission of health and family planning [2017YQ060]
- Fudan University
- Open Project Program of Key Lab of Smart Drug Delivery, Fudan University, Ministry of Education of China [SDD2017-01]
Multiple sclerosis is an autoimmune neurodegenerative disease, which usually caused by inflammation, demyelination, and axonal injury. The currently available medications for multiple sclerosis do not directly promote myelin sheath repair. Therefore, many researches have attempted to achieve better therapeutic effects through promoting remyelination. Natural products not only alleviate clinical symptoms, but also have the unique advantages of protecting and repairing effects on nervous system. We here present a systematic review on published papers about treating multiple sclerosis by natural products, aiming to provide comprehensive information on natural products in the treatment of multiple sclerosis.
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