期刊
HUMAN BRAIN MAPPING
卷 40, 期 10, 页码 2867-2883出版社
WILEY
DOI: 10.1002/hbm.24565
关键词
dorsal stream; functional connectivity; functional magnetic resonance imaging; left supramarginal gyrus; manipulable object representations; tool processing; tool transport; tool use; ventral stream
资金
- National Institutes of Health [R01 NS099061, 5T32HD071844-05]
Interacting with manipulable objects (tools) requires the integration of diverse computations supported by anatomically remote regions. Previous functional neuroimaging research has demonstrated the left supramarginal (SMG) exhibits functional connectivity to both ventral and dorsal pathways, supporting the integration of ventrally-mediated tool properties and conceptual knowledge with dorsally-computed volumetric and structural representations of tools. This architecture affords us the opportunity to test whether interactions between the left SMG, ventral visual pathway, and dorsal visual pathway are differentially modulated when participants plan and generate tool-directed gestures emphasizing functional manipulation (tool use gesturing) or structure-based grasping (tool transport gesturing). We found that functional connectivity between the left SMG, ventral temporal cortex (bilateral fusiform gyri), and dorsal visual pathway (left superior parietal lobule/posterior intraparietal sulcus) was maximal for tool transport planning and gesturing, whereas functional connectivity between the left SMG, left ventral anterior temporal lobe, and left frontal operculum was maximal for tool use planning and gesturing. These results demonstrate that functional connectivity to the left SMG is differentially modulated by tool use and tool transport gesturing, suggesting that distinct tool features computed by the two object processing pathways are integrated in the parietal lobe in the service of tool-directed action.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据