4.6 Article

Bioconcentration and ecotoxicity of sulfadiazine in the aquatic midge Chironomus riparius

期刊

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.etap.2018.12.021

关键词

Antibiotic; Bioconcentration; Oxidative stress; Genetic biomarkers

资金

  1. National Natural Science Foundation of China [51709002, 51609001, 31572033, 51809226]
  2. Natural Science Fund for Distinguished Young Scholars of Anhui Province [1808085J16]

向作者/读者索取更多资源

Although sulfadiazine (SDZ) is widespread in aquatic environments, information regarding the effects of SDZ on aquatic insects is still limited. In the present study, the bioconcentration and the effects of SDZ on the antioxidant system and the expression of endocrine and stress-related genes in Chironomus riparius larvae were investigated. The larvae were exposed to SDZ at the nominal concentrations of 2, 20 and 200 mu g/L for 48 h. The results showed that SDZ was taken up by C. riparius despite presenting low bioconcentration factor values (0.99-3.92). In addition, superoxide dismutase activity was markedly reduced compared with the control group, whereas the levels of malondialdehyde were not significantly affected by SDZ. Moreover, the mRNA expression of genes related to heat shock proteins (Hsp70 and Hsp27) and ecdysone pathway (EcR and E74) were significantly up-regulated following all SDZ treatments. In aggregate, our work provides novel and interesting results regarding the potential biochemical and genetic effects of SDZ on freshwater insects.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据