4.7 Review

Muller cells as a target for retinal therapy

期刊

DRUG DISCOVERY TODAY
卷 24, 期 8, 页码 1483-1498

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2019.01.023

关键词

-

向作者/读者索取更多资源

Muller cells are specialized glial cells that span the entire retina from the vitreous cavity to the subretinal space. Their functional diversity and unique radial morphology render them particularly interesting targets for new therapeutic approaches. In this review, we reflect on various possibilities for selective Willer cell targeting and describe how some of their cellular mechanisms can be used for retinal neuroprotection. Intriguingly, cross-species investigation of their properties has revealed that Muller cells also have an essential role in retinal regeneration. Although many questions regarding this subject remain, it is clear that Muller cells have unique characteristics that make them suitable targets for the prevention and treatment of numerous retinal diseases.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据