期刊
DIABETES CARE
卷 42, 期 6, 页码 1129-1131出版社
AMER DIABETES ASSOC
DOI: 10.2337/dc18-1631
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资金
- Joslin Clinical Research Center
OBJECTIVETo objectively evaluate adherence to timing and dosing of insulin by using Bluetooth pen caps and examine factors related to adherence.RESEARCH DESIGN AND METHODSBluetooth-enabled insulin pen caps were used in younger (ages 18-35 years) and older (ages >= 65 years) adults on two or more insulin injections per day.RESULTSWe evaluated 75 participants with diabetes, 42 younger (29 4 years) and 33 older (73 +/- 7 years). Nonadherence was found in 24% of bolus (Apidra) doses and 36% of basal (Lantus) doses. We divided participants into tertiles on the basis of overall adherence, with the most adherent tertile having 85% dose adherence compared with 49% in the least adherent tertile (P < 0.001). Participants in the most adherent tertile had better glycemic control than those in the least adherent tertile (7.7 +/- 1.1% [61 +/- 12 mmol/mol] vs. 8.6 +/- 1.5% [70 +/- 16.4 mmol/mol], P < 0.03).CONCLUSIONSNonadherence to insulin dosing and timing can be objectively assessed by Bluetooth pen caps and is associated with poor glycemic control.
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