期刊
CURRENT MEDICINAL CHEMISTRY
卷 27, 期 21, 页码 3534-3554出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867326666190301143952
关键词
Atherosclerosis; cardiovascular diseases; nanomedicine; drug delivery system; diagnosis; treatment; theranostics; scaffolds
资金
- Fundamental Research Funds for the Central Universities of China [2672018ZYGX2018J097]
Atherosclerosis is the leading inducement of cardiovascular diseases, which ranks the first cause of global deaths. It is an arterial disease associated with dyslipidemia and changes in the composition of the vascular wall. Besides invasive surgical strategy, the current conservative clinical treatment for atherosclerosis falls into two categories, lipid regulating-based therapy and anti-inflammatory therapy. However, the existing strategies based on conventional drug delivery systems have shown limited efficacy against disease development and plenty of side effects. Nanomedicine has great potential in the development of targeted therapy, controlled drug delivery and release, the design of novel specific drugs and diagnostic modalities, and biocompatible scaffolds with multifunctional characteristics, which has led to an evolution in the diagnosis and treatment of atherosclerosis. This paper will focus on the latest nanomedicine strategies for atherosclerosis diagnosis and treatment as well as discussing the potential therapeutic targets during atherosclerosis progress, which could form the basis of development of novel nanoplatform against atherosclerosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据