期刊
CURRENT BIOLOGY
卷 29, 期 5, 页码 R156-R158出版社
CELL PRESS
DOI: 10.1016/j.cub.2019.01.036
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资金
- NIGMS NIH HHS [R35 GM122475] Funding Source: Medline
Abnormal chromosome number, or aneuploidy, is common in early mammalian embryos, although the underlying cell biological basis is still incompletely understood. New research reveals that cells often fail to wait for all chromosomes to properly attach to the spindle machinery before segregation, explaining why early embryonic cell cycles are so error-prone.
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