4.7 Article

Emergence of Low-level Delamanid and Bedaquiline Resistance During Extremely Drug-resistant Tuberculosis Treatment

期刊

CLINICAL INFECTIOUS DISEASES
卷 69, 期 7, 页码 1229-1231

出版社

OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciz074

关键词

XDR-tuberculosis; delamanid resistance; bedaquiline resistance

资金

  1. Institute for Microbiology, Immunology and Laboratory Medicine, Helios Klinikum Emil von Behring
  2. SYNLAB Gauting, SYNLAB MVZ Humane Genetik
  3. Research Center Borstel
  4. German Center for Infection Research
  5. National Reference Laboratory for Mycobacteria
  6. Deutsche Forschungsgemeinschaft (German Research Foundation), Germany's Excellence Strategy [EXC 22167-390884018]
  7. Leibniz Science Campus EvoLUNG (Evolutionary Medicine of the Lung)

向作者/读者索取更多资源

Two new drugs, delamanid and bedaquiline, have recently been approved for treatment of multidrug-resistant and extensively drug-resistant (XDR) tuberculosis. Here, we report a case of clofazimine, bedaquiline, and low-level delamanid resistances acquired during treatment of a patient with XDR tuberculosis.

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