4.5 Review

Acidosis promotes tumorigenesis by activating AKT/NF-κB signaling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells

Jose Teixeira et al.

REDOX BIOLOGY (2018)

Article Multidisciplinary Sciences

Systems analysis of intracellular pH vulnerabilities for cancer therapy

Erez Persi et al.

NATURE COMMUNICATIONS (2018)

Review Oncology

Tumour acidosis: from the passenger to the driver's seat

Cyril Corbet et al.

NATURE REVIEWS CANCER (2017)

Article Biochemistry & Molecular Biology

Regulation of breast tumorigenesis through acid sensors

S. C. Gupta et al.

ONCOGENE (2016)

Article Oncology

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

Veronica Estrella et al.

CANCER RESEARCH (2013)

Article Oncology

Acidic pH via NF-κB favours VEGF-C expression in human melanoma cells

Silvia Peppicelli et al.

CLINICAL & EXPERIMENTAL METASTASIS (2013)

Review Neurosciences

Acid-sensing ion channels in pain and disease

John A. Wemmie et al.

NATURE REVIEWS NEUROSCIENCE (2013)

Review Oncology

Targeting the PI3K-AKT-mTOR signaling network in cancer

Khurum H. Khan et al.

CHINESE JOURNAL OF CANCER (2013)

Review Physiology

Acidic tumor microenvironment and pH-sensing G protein-coupled receptors

Calvin R. Justus et al.

FRONTIERS IN PHYSIOLOGY (2013)

Review Physiology

pH sensing and regulation in cancer

Mehdi Damaghi et al.

FRONTIERS IN PHYSIOLOGY (2013)

Article Oncology

Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress

Gregory LaMonte et al.

CANCER & METABOLISM (2013)

Article Oncology

Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments

Jonathan W. Wojtkowiak et al.

CANCER RESEARCH (2012)

Article Pharmacology & Pharmacy

Physiological and Pathological Functions of Acid-Sensing Ion Channels in the Central Nervous System

Xiang-Ping Chu et al.

CURRENT DRUG TARGETS (2012)

Article Biochemistry & Molecular Biology

Glioma-specific Cation Conductance Regulates Migration and Cell Cycle Progression

Arun K. Rooj et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Cell Biology

Crosstalk of reactive oxygen species and NF-kappa B signaling

Michael J. Morgan et al.

CELL RESEARCH (2011)

Article Biochemistry & Molecular Biology

A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes

Isabel Rodriguez-Escudero et al.

HUMAN MOLECULAR GENETICS (2011)

Article Multidisciplinary Sciences

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

Christopher J. Bohlen et al.

NATURE (2011)

Review Biophysics

Imaging pH and metastasis

Arig Ibrahim Hashim et al.

NMR IN BIOMEDICINE (2011)

Article Multidisciplinary Sciences

Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells

Anne Riemann et al.

PLOS ONE (2011)

Review Cell Biology

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

D. R. Gough et al.

CELL DEATH & DISEASE (2011)

Article Cell Biology

Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells

Wen-Shuo Chung et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)

Review Biochemistry & Molecular Biology

Inhibiting NF-kappa B activation by small molecules as a therapeutic strategy

Subash C. Gupta et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Activation of P-glycoprotein (Pgp)-mediated drug efflux by extracellular acidosis: in vivo imaging with 68Ga-labelled PET tracer

Oliver Thews et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2010)

Article Biochemistry & Molecular Biology

Knockdown of ASIC1 and Epithelial Sodium Channel Subunits Inhibits Glioblastoma Whole Cell Current and Cell Migration

Niren Kapoor et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

Eric B. Gonzales et al.

NATURE (2009)

Review Biotechnology & Applied Microbiology

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Dunyaporn Trachootham et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Oncology

Acid treatment of melanoma cells selects for invasive phenotypes

Raymond E. Moellering et al.

CLINICAL & EXPERIMENTAL METASTASIS (2008)

Review Biochemistry & Molecular Biology

PI3K pathway alterations in cancer: variations on a theme

T. L. Yuan et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH

Jayasankar Jasti et al.

NATURE (2007)

Article Oncology

Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer

Lisam Shanjukumar Singh et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)

Article Neurosciences

A tarantula peptide against pain via ASIC1a channels and opioid mechanisms

Michel Mazzuca et al.

NATURE NEUROSCIENCE (2007)

Article Biochemistry & Molecular Biology

Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells

Wanda H. Vila-Carriles et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Review - Receptors for protons or lipid messengers or both?

Klaus Seuwen et al.

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2006)

Article Biochemistry & Molecular Biology

Identification of acid-sensing ion channels in bone

H Jahr et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Review Oncology

Nuclear factor-κ-B:: The enemy within

BB Aggarwal

CANCER CELL (2004)

Review Oncology

Why do cancers have high aerobic glycolysis?

RA Gatenby et al.

NATURE REVIEWS CANCER (2004)

Article Multidisciplinary Sciences

Proton-sensing G-protein-coupled receptors

MG Ludwig et al.

NATURE (2003)

Article Biochemistry & Molecular Biology

Acid-sensing ion channels in malignant gliomas

BK Berdiev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cells

Q Shi et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2000)