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The advanced role of carbon quantum dots in nanomedical applications

期刊

BIOSENSORS & BIOELECTRONICS
卷 141, 期 -, 页码 -

出版社

ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2019.02.059

关键词

Carbon quantum dots; Bio imaging; Theranostics; Drug/gene delivery; Bactericidal

资金

  1. Department of Science and Technology [GAP 375]
  2. National Research Foundation of Korea (NRF) - Ministry of Science, ICT and Future Planning [2016R1E1A1A01940995]
  3. Cooperative Research Program for Agriculture Science & Technology Development Rural Development Administration, Republic of Korea [PJ014297]

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Carbon quantum dots (CQDs) have emerged as a potential material in the diverse fields of biomedical applications due to their numerous advantageous properties including fluorescence, water solubility, biocompatibility, low toxicity, small size and ease of modification, inexpensive scale-up production, and versatile conjugation with other nanoparticles. Thus, CQDs became a preferable choice in various biomedical applications such as nanocarriers for drugs, therapeutic genes, photosensitizers, and antibacterial molecules. Further, their potentials have also been verified in multifunctional diagnostic platforms, cellular and bacterial bio-imaging, development of theranostics nanomedicine, etc. This review provides a concise insight into the progress and evolution in the field of CQD research with respect to methods/materials available in bio-imaging, theranostics, cancer/gene therapy, diagnostics, etc. Further, our discussion is extended to explore the role of CQDs in nanomedicine which is considered to be the future of biomedicine. This study will thus help biomedical researchers in tapping the potential of CQDs to overcome various existing technological challenges.

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