4.7 Article

ppsPCP: a plant presence/absence variants scanner and pan-genome construction pipeline

期刊

BIOINFORMATICS
卷 35, 期 20, 页码 4156-4158

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OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz168

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资金

  1. National Key Research and Development Program of China [2016YFD0100904, 2018YFD1000101]
  2. National Natural Science Foundation of China [31871269, 31571351]
  3. Fundamental Research Funds for the Central Universities [2662017PY043]

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Since the idea of pan-genomics emerged several tools and pipelines have been introduced for prokaryotic pan-genomics. However, not a single comprehensive pipeline has been reported which could overcome multiple challenges associated with eukaryotic pan-genomics. To aid the eukaryotic pan-genomic studies, here we present ppsPCP pipeline which is designed for eukaryotes especially for plants. It is capable of scanning presence/absence variants (PAVs) and constructing a fully annotated pan-genome. We believe with these unique features of PAV scanning and building a pan-genome together with its annotation, ppsPCP will be useful for plant pan-genomic studies and aid researchers to study genetic/phenotypic variations and genomic diversity.

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