4.7 Article

G4Hunter web application: a web server for G-quadruplex prediction

期刊

BIOINFORMATICS
卷 35, 期 18, 页码 3493-3495

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz087

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资金

  1. Czech Science Foundation [18-15548S]
  2. SYMBIT project from ERDF [CZ. 02.1.01/0.0/0.0/15_ 003/0000477]

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Motivation: Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community. Results: We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web application includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export.

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