期刊
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
卷 39, 期 5, 页码 841-849出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/ATVBAHA.118.311756
关键词
atherosclerosis; fluorine; inflammation; magnetic resonance imaging
资金
- Dutch Technology Foundation TTW (Toegepaste en Technische Wetenschappen)
- American Heart Association Scientist Development [16SDG27250090]
- VENI Grant from the Dutch Technology Foundation TTW [14348]
- Dutch Technology Foundation TTW (MUSICIAN [Fluorine Magnetic Resonance and Ultrasound Imaging of Cardiac Inflammation]) [14716]
Atherosclerosis is a prevalent disease affecting a large portion of the population at one point in their lives. There is an unmet need for noninvasive diagnostics to identify and characterize at-risk plaque phenotypes noninvasively and in vivo, to improve the stratification of patients with cardiovascular disease, and for treatment evaluation. Magnetic resonance imaging is uniquely positioned to address these diagnostic needs. However, currently available magnetic resonance imaging methods for vessel wall imaging lack sufficient discriminative and predictive power to guide the individual patient needs. To address this challenge, physicists are pushing the boundaries of magnetic resonance atherosclerosis imaging to increase image resolution, provide improved quantitative evaluation of plaque constituents, and obtain readouts of disease activity such as inflammation. Here, we review some of these important developments, with specific focus on emerging applications using high-field magnetic resonance imaging, the use of quantitative relaxation parameter mapping for improved plaque characterization, and novel F-19 magnetic resonance imaging technology to image plaque inflammation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据