期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 58, 期 22, 页码 7335-7340出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201901880
关键词
colloidal nanoclusters; FRET; multicompartment micelles; patchy particles; triblock copolymers
资金
- ARC [DP160101172]
Recent years have seen an increased interest in the use of ABC triblock terpolymers to bottom-up assemble multicompartment patchy nanoparticles. Despite these experimental and theoretical efforts, the applications of polymer-based patchy nanoparticles remain rather limited. One of the major challenges that eclipses their potential is the lack of knowledge to selectively encapsulate cargoes within different compartments that are separated in the nanometer length scale. Here, strategies are reported to segregate two chemically distinct molecules in either the patches or core compartment of patchy nanoparticles that bear a (bioactive) sugar corona. The potential use of these bioactive patchy nanoparticles containing compartmentalized cargoes for simultaneous drug delivery with real-time release monitoring capabilities is further demonstrated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据