期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 58, 期 38, 页码 13232-13252出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201900594
关键词
Cerenkov radiation; nanomedicine; radioactivation; radionuclides; theranostics
资金
- University of Wisconsin-Madison
- National Institutes of Health [P30CA014520]
- Brazilian Science without Borders Program (SwB-CNPq)
Radio-nanomedicine, or the use of radiolabeled nanoparticles in nuclear medicine, has attracted much attention in the last few decades. Since the discovery of Cerenkov radiation and its employment in Cerenkov luminescence imaging, the combination of nanomaterials and Cerenkov radiation emitters has been revolutionizing the way nanomaterials are perceived in the field: from simple inert carriers of radioactivity to activatable nanomaterials for both diagnostic and therapeutic applications. Herein, we provide a comprehensive review on the types of nanomaterials that have been used to interact with Cerenkov radiation and the gamma and beta scintillation of radionuclides, as well as on their biological applications.
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