期刊
ANALYTICAL CHEMISTRY
卷 91, 期 6, 页码 4039-4046出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.8b05552
关键词
-
资金
- National Natural Science Foundation of China [21675024, 21804021]
- Program for Innovative Leading Talents in Fujian Province [2016B016]
- Joint Funds for the Innovation of Science and Technology, Fujian Province [2016Y9056]
- Natural Science Foundation of Fujian Province [2017J01575]
- Science and Technology Project of Fujian Province [2018L3008]
- Startup Fund for scientific research, Fujian Medical University [2017XQ1014]
Although it has been demonstrated that rare-earth elements (REEs) disturb and alter the catalytic activity of numerous natural enzymes, their effects on nanomaterial-based artificial enzymes (nanozymes) have been seldom explored. In this work, the influence of REEs on the peroxidase-like activity of bare gold nanoparticles (GNPs) is investigated for the first time, and a new type of Ce3+-activated peroxidase mimetic activity of GNPs is obtained. The introduced Ce3+ can be bound to the bare GNP surface rapidly through electrostatic attraction, after which it donates Films its electron to the bare GNP. As H2O2 is a good electron scavenger, more (OH)-O-center dot radicals are generated on the surfaces of the bare GNPs, which can considerably enhance TMB oxidation. Due to its redox cycling ability, the activation effect of Ce3+ is proved to be more efficient in comparison to those of the other reported metal ion activators (e.g., Bi3+, Hg2+, and Pb2+). In addition, it is determined that Ce(3+)should directly contact with the gold core to trigger its activation effect. When the surface states of the bare GNPs are altered, the Ce3+-stimulated effect is strongly inhibited. Furthermore, a novel colorimetric method for Ce3+ is developed, on the basis of its enhancing effect on the peroxidase mimetic activity of bare GNPs. The sensitivity of this newly developed method for Ce3+ is excellent with a limit of detection as low as 2.2 nM. This study not only provides an effective GNP-based peroxidase mimic but also contributes in realizing new applications for nanozymes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据