期刊
ANALYTICAL BIOCHEMISTRY
卷 566, 期 -, 页码 146-150出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ab.2018.11.016
关键词
Cytokines; Earlobe capillary; Dried plasma spots; Extension assay; Inflammation protein biomarkers
资金
- Marietta Blau scholarship - OeAD
- BMBWF
- University of Vienna
- GastricGlycoExplorer grant of the European Commission's Seventh Framework Programme [316929]
In this study, levels of inflammatory protein biomarkers in venous plasma, plasma derived from capillary blood from the earlobe, and capillary plasma stored as dried plasma spots (DPS) were compared. Samples from 12 male individuals were assessed with a panel of 92 inflammation-related proteins using multiplex proximity extension assay. Correlations between sample types varied greatly between analytes. A high correlation of rho > 0.8 was observed between capillary plasma and DPS for 32 analytes. At this level of correlation, 13 analytes correlated between venous and capillary plasma and 5 analytes in the comparison of venous blood with DPS.
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