期刊
ANALYTICA CHIMICA ACTA
卷 1066, 期 -, 页码 69-78出版社
ELSEVIER
DOI: 10.1016/j.aca.2019.03.013
关键词
Gastric juice; Household pesticides; Point-of-care; Emergency management; Ambient mass spectrometry
资金
- NSYSU-KMU JOINT RESEARCH PROJECT [NSYSUKMU 107-P020, 107-I004]
- Kaohsiung Medical University Aim for the Top Universities Grant [KMU-TP105G00, KMU-TP105G01, KMU-TP105G02]
- Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project, Ministry of Education in Taiwan
In order to provide timely emergency management for the patients accidently or intentionally ingested of household pesticides, it is crucial to develop a point-of-care analytical technique for early ex vivo identification of swallowed pesticides. In this study, probe sampling combined with electrospray laser desorption ionization/mass spectrometry (ELDI/MS) was performed to rapidly detect spiked non-volatile household pesticides in the gastric juice drained from the patients during lavage. Since no sample pretreatment is required, probe sampling is fast, and high thermal energy for analyte desorption is provided; ELDI/MS detects the household pesticides in gastric juice within 30 s. The detection limits of the household pesticides were found to be 0.05-1 mg/L, this makes ELDI/MS combined with probe sampling a novel and efficient analytical tool for providing important toxicological information to ensure an appropriate emergency medical response. (C) 2019 Published by Elsevier B.V.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据