期刊
AMERICAN JOURNAL OF HYPERTENSION
卷 29, 期 10, 页码 1173-1178出版社
OXFORD UNIV PRESS
DOI: 10.1093/ajh/hpw063
关键词
arterial blood pressure; blood pressure; blood pressure determination; diagnostic equipment; hemodynamics; hypertension; oscillometry; pulse wave analysis
资金
- National Health and Medical Research Council of Australia (NHMRC) [1044551]
- NHMRC Career Development Fellowship [1045373]
- National Heart Foundation Postdoctoral Fellowship [100134]
New techniques that measure central blood pressure (BP) using an upper arm cuff-based approach require performance assessment. The aim of this study was to compare a cuff-based device (Cuff(CBP)) to estimate central BP indices (systolic BP (SBP), diastolic BP (DBP), pulse pressure (PP), augmentation pressure (AP), augmentation index (AIx)) with noninvasive radial tonometry (Ton(CBP)). Consecutive Cuff(CBP) (SphygmoCor Xcel) and Ton(CBP) (SphygmoCor 8.1) duplicate recordings were measured in 182 people with treated hypertension (aged 61 +/- 7 years, 48% male). Agreement between methods was assessed using standard calibration with brachial SBP and DBP (measured with the Xcel device), as well as with brachial mean arterial pressure (MAP; 40% form factor method) and DBP. The mean difference +/- SD for central SBP (cSBP), central DBP (cDBP), and central PP (cPP) between methods were -0.89 +/- 3.48mm Hg (intra-class correlation (ICC) 0.977; 95% confidence interval (CI) 0.973-0.982), -0.50 +/- 1.54mm Hg (ICC 0.992, 95% CI 0.987-0.993), and -0.42 +/- 3.57mm Hg (ICC 0.966, 95% CI 0.958-0.972), indicating good agreement. Wider limits of agreement were observed for central AP (cAP) and central AIx (cAIx) (-0.91 +/- 5.31mm Hg; ICC 0.802; 95% CI 0.756-0.839, -0.99 +/- 10.91%; ICC 0.749; 95% CI 0.691-0.796). Re-calibration with brachial MAP and DBP resulted in an overestimation of cSBP with Cuff(CBP) compared with Ton(CBP) (8.58 +/- 19.06mm Hg, ICC 0.164, 95% CI -0.029 to 0.321). cSBP, cDBP, and cPP derived from Cuff(CBP) are substantially equivalent to Ton(CBP,) although the level of agreement is dependent on calibration method. Further validity testing of Cuff(CBP) by comparison with invasively measured central BP will be required.
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