期刊
BIOFOULING
卷 31, 期 1, 页码 101-122出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/08927014.2014.997226
关键词
antifouling; biofouling; marine natural products; antifouling compounds
资金
- China Ocean Mineral Resources Research and Development Association [DY125-15-T-02]
- Sanya Institute of Deep Sea Science and Engineering [SIDSSE-201206]
- GRC grant from Hong Kong Special Administrative Region [GRF661611]
- King Abdullah University of Science and Technology [SA-C0040/UK-C0016]
This review covers 214 marine natural compounds and 23 of their synthetic analogs, which were discovered and/or synthesized from mid-2009 to August 2014. The antifouling (AF) compounds reported have medium to high bioactivity (with a threshold of EC50 < 15.0 mg ml(-1)). Among these compounds, 82 natural compounds were identified as new structures. All the compounds are marine-derived, demonstrating that marine organisms are prolific and promising sources of natural products that may be developed as environmentally friendly antifoulants. However, this mini-review excludes more than 200 compounds that were also reported as AF compounds but with rather weak bioactivity during the same period. Also excluded are terrestrial-derived AF compounds reported during the last five years. A brief discussion on current challenges in AF compound research is also provided to reflect the authors' own views in terms of future research directions.
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