期刊
BIOESSAYS
卷 37, 期 10, 页码 1095-1105出版社
WILEY-BLACKWELL
DOI: 10.1002/bies.201500065
关键词
ribosomal proteins; RNA polymerase III; stress response; SUMO; transcription; tRNA; UBLs
资金
- Norwegian Research Council [221694, 221920]
- Norwegian Cancer Society [3311782]
The small ubiquitin-like modifier SUMO regulates many aspects of cellular physiology to maintain cell homeostasis, both under normal conditions and during cell stress. Components of the transcriptional apparatus and chromatin are among the most prominent SUMO substrates. The prevailing view is that SUMO serves to repress transcription. However, as we will discuss in this review, this model needs to be refined, because recent studies have revealed that SUMO can also have profound positive effects on transcription.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据