期刊
BIOCONJUGATE CHEMISTRY
卷 26, 期 6, 页码 1000-1003出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.bioconjchem.5b00180
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资金
- National Natural Science Foundation of China
- National Basic Research Program of China (973 Program) [2014CB745100, 2015CB856500]
- Tianjin Municipal Science & Technology Commission [14JCZDJC33400]
The increasing availability of highly active no-carrier-added [F-18]-fluoride makes its use in radiolabeling biomolecules attractive. By incorporating fluorophilic elements (Si, B, and Al) into biomolecules, recent advances offer mild and rapid F-18-labeling approaches without HPLC purification at the radiosynthetic stage while maintaining sufficient specific activity. In this Topical Review, we will discuss the most recent strides in the field.
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