Ultrathin MXene-Micropattern-Based Field-Effect Transistor for Probing Neural Activity

A field-effect transistor (FET) based on ultrathin Ti3C2-MXene micropatterns is developed and utilized as a highly sensitive biosensor. The device is produced with the microcontact printing technique, making use of its unique advantages for easy fabrication. Using the MXene-FET device, label-free probing of small molecules in typical biological environments and fast detection of action potentials in primary neurons is demonstrated.