4.8 Article

Tuning the Drug Loading and Release of DNA-Assembled Gold-Nanorod Superstructures

期刊

ADVANCED MATERIALS
卷 28, 期 38, 页码 8511-8518

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201600773

关键词

cancer; controlled drug release; DNA assembly; gold nanorods; core-satellite; nanotechnology; nanomedicine

资金

  1. Canadian Institute of Health Research [MOP-130143, RMF-111623O]
  2. Natural Sciences and Engineering Research Council (NSERC) [2015-06397]
  3. Prostate Cancer Foundation [D2014-12]
  4. Canadian Breast Cancer Foundation
  5. NSERC

向作者/读者索取更多资源

The use of DNA to assemble inorganic nanoparticles into superstructures is an emerging strategy to build non-toxic delivery vehicles for targeting diseases in the body. The impact of the core-satellite nanosystem design in mediating drug storage, drug release (via heat), and killing of HeLa cells in culture is investigated.

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