期刊
ADVANCED MATERIALS
卷 28, 期 38, 页码 8419-8424出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201602268
关键词
biomaterials; double networks; supramolecular chemistry; tissue engineering
类别
资金
- National Institutes of Health [R01 EB008722, P30 AR050950]
- American Heart Association
Double-network theory is extended to include guest-host interactions, enabling injectability and cytcompatibility of tough hydrogels. Noncovalent interactions are used as a sacrificial network to toughen covalently crosslinked hydrogels formed from hyaluronic acid. Shear thinning of supramolecular bonds allows hydrogel injection and rapid self-healing, while gentle reaction conditions permit cell encapsulation with high viability.
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