期刊
PHARMACEUTICS
卷 10, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/pharmaceutics10040268
关键词
DNA self-assembling; gene delivery; drug delivery; protein delivery; theranostics; nanomedicine
资金
- Spanish Ministerio de Ciencia e Innovacion (MICINN) [CTQ2017-84415-R]
- CIBER-BBN [CB06_01_0019]
- Generalitat de Catalunya [2017/SGR/114]
- Fundacao para a Ciencia e Tecnologia (FCT), Portugal [SFRH/BPD/104544/2014]
- FCT [007630 UID/QUI/00313/2013]
- COMPETE2020-UE
- VI National R + D + I Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions
- Instituto de Salud Carlos III
Molecular self-assembling is ubiquitous in nature providing structural and functional machinery for the cells. In recent decades, material science has been inspired by the nature's assembly principles to create artificially higher-order structures customized with therapeutic and targeting molecules, organic and inorganic fluorescent probes that have opened new perspectives for biomedical applications. Among these novel man-made materials, DNA nanostructures hold great promise for the modular assembly of biocompatible molecules at the nanoscale of multiple shapes and sizes, designed via molecular programming languages. Herein, we summarize the recent advances made in the designing of DNA nanostructures with special emphasis on their application in biomedical research as imaging and diagnostic platforms, drug, gene, and protein vehicles, as well as theranostic agents that are meant to operate in-cell and in-vivo.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据