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Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail
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EMBO JOURNAL (2006)
Autologous morphogen gradients by subtle interstitial flow and matrix interactions
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M. A. Karajannis et al.
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CANCER RESEARCH (2006)
Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model
Matthias Hofmann et al.
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The distribution of the anticancer drug doxorubicin in relation to blood vessels in solid tumors
AJ Primeau et al.
CLINICAL CANCER RESEARCH (2005)
Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro
CP Ng et al.
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Tensional homeostasis and the malignant phenotype
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CANCER CELL (2005)
Inactivation of nuclear factor κB by soy isoflavone genistein contributes to increased apoptosis mduced by chemotherapeutic agents in human cancer cells
YW Li et al.
CANCER RESEARCH (2005)
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
DC Radisky et al.
NATURE (2005)
Mathematical modelling of flow in 2D and 3D vascular networks:: Applications to anti-angiogenic and chemotherapeutic drug strategies
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MATHEMATICAL AND COMPUTER MODELLING (2005)
The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed
L Riol-Blanco et al.
JOURNAL OF IMMUNOLOGY (2005)
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
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Tumoral drug metabolism: Overview and its implications for cancer therapy
M Michael et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine
K Yokoi et al.
CLINICAL CANCER RESEARCH (2004)
Quantitative assessment of uptake and distribution of iron oxide particles (NC100150) in human melanoma xenografts by contrast-enhanced MRI
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MAGNETIC RESONANCE IN MEDICINE (2004)
High interstitial fluid pressure -: An obstacle in cancer therapy
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NATURE REVIEWS CANCER (2004)
Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles
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CANCER BIOLOGY & THERAPY (2004)
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
HIF-1 and p53:: communication of transcription factors under hypoxia
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2004)
Regulation of matrix biology by matrix metalloproteinases
JD Mott et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFP/ALK5 signaling
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MOLECULAR CELL (2003)
PAKI phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
JK Slack-Davis et al.
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MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transforming growth factor-β1 (TGF-β)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-β-activated kinase 1 and mitogen-activated protein kinase kinase 3
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MOLECULAR BIOLOGY OF THE CELL (2003)
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxiainducible factor-1 and reactive oxygen species
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FASEB JOURNAL (2003)
Tumor hypoxia: A target for selective cancer therapy
S Kizaka-Kondoh et al.
CANCER SCIENCE (2003)
A paradigm for therapy-induced microenvironmental changes in solid tumors leading to drug resistance
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DIFFERENTIATION (2002)
Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and progression
E Ioachim et al.
EUROPEAN JOURNAL OF CANCER (2002)
β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
VM Weaver et al.
CANCER CELL (2002)
Proteolysis of latent transforming growth factor-β (TGF-β)-binding protein-1 by osteoclasts -: A cellular mechanism for release of TGF-β from bone matrix
SL Dallas et al.
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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
G Bergers et al.
NATURE CELL BIOLOGY (2000)
Multidrug resistance (MDR) in cancer - Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs
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Serine phosphorylation of STATs
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ONCOGENE (2000)
Hypoxia induces hexokinase II gene expression in human lung cell line A549
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AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)