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Shelley L. Forrest et al.
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ANNALS OF NEUROLOGY (2016)
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EMBO MOLECULAR MEDICINE (2016)
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Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies
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Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections
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ACTA NEUROPATHOLOGICA (2015)
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ACTA NEUROPATHOLOGICA (2015)
mTor mediates tau localization and secretion: Implication for Alzheimer's disease
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NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2015)
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NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2015)
Tau Monoclonal Antibody Generation Based on Humanized Yeast Models IMPACT ON TAU OLIGOMERIZATION AND DIAGNOSTICS
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JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model
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ACTA NEUROPATHOLOGICA (2014)
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
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ACTA NEUROPATHOLOGICA (2014)
Neuronal activity regulates extracellular tau in vivo
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JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
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NEURON (2014)
Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein
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PLOS ONE (2014)
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ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
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FRONTIERS IN NEUROLOGY (2013)
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FEBS LETTERS (2012)
Clinical, Neuropathological, and Biochemical Characterization of the Novel Tau Mutation P332S
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JOURNAL OF ALZHEIMERS DISEASE (2012)
Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
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JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
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JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes
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NEURON (2012)
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PLOS ONE (2012)
Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion
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PLOS ONE (2012)
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EMBO JOURNAL (2011)
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
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NEURON (2010)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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NATURE CELL BIOLOGY (2009)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps
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The potential for β-structure in the repeat domain of Tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
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Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L Tau but not wild-type Tau
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Epitope mapping of mAbs AT8 and Tau5 directed against hyperphosphorylated regions of the human tau protein
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome
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Tau aggregation is driven by a transition from random coil to beta sheet structure
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease
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NEUROLOGY (2003)
Phosphorylated serine 199 of microtubule-associated protein tau is a neuronal epitope abundantly expressed in youth and an early marker of tau pathology
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ACTA NEUROPATHOLOGICA (2003)
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ACTA NEUROPATHOLOGICA (2002)
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local β-structure
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
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BIOCHEMISTRY (2000)
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BRAIN RESEARCH REVIEWS (2000)
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JOURNAL OF NEUROSCIENCE (2000)